Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9104540 | 0.88 | KMT2A (0.49) | KMT2AMEN1HDAC1HDAC6HDAC3 | |
| SCHEMBL9106473 | 0.80 | P2RX4 (0.37) | HDAC6HDAC3 | |
| SCHEMBL9100589 | 0.77 | KMT2A (0.49) | KMT2AMEN1HDAC1HDAC6HDAC3 | |
| SCHEMBL21693081 | 0.77 | KMT2A (0.51) | KMT2AMEN1HDAC1HDAC6HDAC3 | |
| SCHEMBL28953196 | 0.72 | KMT2A (0.50) | KMT2AMEN1HDAC1HDAC6HDAC3 | |
| SCHEMBL28577558 | 0.69 | KDM1A (0.50) | KMT2AMEN1HDAC6KDM1AMAOA | |
| SCHEMBL8965779 | 0.68 | MAOA (0.41) | KDM1AMAOABCHEGAAMAPT | |
| SCHEMBL9104148 | 0.68 | P2RX4 (0.40) | KMT2AMEN1MAOAMAPT | |
| SCHEMBL14614806 | 0.67 | CYP1A2 (0.49) | KMT2AMEN1GAA | |
| SCHEMBL2498937 | 0.66 | SMN1; SMN2 (0.51) | KMT2AMEN1HDAC6KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |