Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 4/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9104148 | 0.88 | P2RX4 (0.40) | P2RX4P2RX1ADRA2AADRA2BADRA2C | |
| SCHEMBL9106583 | 0.80 | KMT2A (0.47) | HDAC3HDAC6 | |
| SCHEMBL9102529 | 0.77 | LMNA (0.42) | P2RX4 | |
| SCHEMBL21691991 | 0.77 | P2RX4 (0.37) | P2RX4 | |
| SCHEMBL11420554 | 0.70 | KDM4E (0.43) | P2RX4NISCH | |
| SCHEMBL9104540 | 0.68 | KMT2A (0.49) | MGLLHDAC3HDAC6 | |
| SCHEMBL13023981 | 0.68 | LMNA (0.36) | P2RX4 | |
| SCHEMBL20172203 | 0.67 | P2RX4 (0.37) | P2RX4NISCH | |
| SCHEMBL14614806 | 0.67 | CYP1A2 (0.49) | — | |
| SCHEMBL30462881 | 0.66 | SMN1; SMN2 (0.47) | P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9632034-B2 | Fluorogenic and chromogenic substrate | LI-COR, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-20160266045-A1 | FLUOROGENIC AND CHROMOGENIC SUBSTRATE | LI-COR, INC. (US) | 2016-09-15 | — | — | US | disclosed |
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |