Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928398 | 0.88 | GAA (0.40) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| SCHEMBL3927048 | 0.85 | GAA (0.39) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| SCHEMBL9738451 | 0.85 | HPGD (0.37) | TAS1R3TAS1R1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8794253 | 0.83 | MAPT (0.37) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| SCHEMBL28814775 | 0.80 | RAB9A (0.41) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| SCHEMBL28814793 | 0.80 | RAB9A (0.41) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| SCHEMBL7760354 | 0.80 | RAB9A (0.41) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| SCHEMBL3929831 | 0.78 | GAA (0.39) | HPGDMAPTTSHRL3MBTL1ALDH1A1 | |
| SCHEMBL3924427 | 0.76 | GAA (0.38) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL13956712 | 0.75 | GAA (0.39) | NPC1RAB9ASMN1; SMN2HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5474919-A | Bioconversion process for the synthesis of transhydroxy sulfone by Rhodotorula rubra or Rhodotorula piliminae | MERCK & CO., INC. (US) | 1995-12-12 | — | — | US | disclosed |