Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.52 |
| ▸ | BMP1 | P13497 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | GNPAT | O15228 | 2/20 | 0.45 |
| ▸ | GLP1R | P43220 | 3/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91076 | 0.92 | NOD1 (0.61) | NOD1EPHX2GNPATFOLH1 | |
| SCHEMBL27322925 | 0.89 | NOD1 (0.65) | NOD1EPHX2GNPATFOLH1 | |
| SCHEMBL12982610 | 0.89 | NOD1 (0.65) | NOD1EPHX2GNPATFOLH1 | |
| SCHEMBL16257666 | 0.89 | NOD1 (0.65) | NOD1EPHX2GNPATFOLH1 | |
| SCHEMBL72619 | 0.89 | NOD1 (0.65) | NOD1EPHX2GNPATFOLH1 | |
| SCHEMBL13641019 | 0.89 | NOD1 (0.65) | NOD1EPHX2GNPATFOLH1 | |
| SCHEMBL13974161 | 0.89 | NOD1 (0.65) | NOD1EPHX2GNPATFOLH1 | |
| SCHEMBL18573773 | 0.89 | NOD1 (0.65) | NOD1EPHX2GNPATFOLH1 | |
| SCHEMBL12980909 | 0.89 | NOD1 (0.65) | NOD1EPHX2GNPATFOLH1 | |
| SCHEMBL14805462 | 0.89 | NOD1 (0.65) | NOD1EPHX2GNPATFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129343-B2 | Acylated GLP-1 compounds | NOVO NORDISK A/S (DK) | 2012-03-06 | — | — | US | disclosed |
| US-20090156478-A1 | Acylated GLP-1 Compounds | NOVO NORDISK A/S (DK) | 2009-06-18 | — | — | US | disclosed |
| US-20090156478-A1 | Acylated GLP-1 Compounds | NOVO NORDISK A/S (DK) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156478-A1 | Acylated GLP-1 Compounds | GLP1R, GIPR, GCGR | NOD1 1340/4885BMP1 1120/4885EPHX2 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.