SCHEMBL12982610

SCHEMBL12982610

CNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 9/20 0.65
GNPAT O15228 1/20 0.50
FOLH1 Q04609 2/20 0.49
RIMKLA Q8IXN7 1/20 0.49
NAALAD2 Q9Y3Q0 1/20 0.49
SLC6A5 Q9Y345 1/20 0.46
PLA2G2C Q5R387 1/20 0.45
PLA2G10 O15496 1/20 0.44
KMT2A Q03164 1/20 0.44
EPHX2 P34913 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14805462 1.00 NOD1 (0.65) NOD1GNPATFOLH1RIMKLANAALAD2
SCHEMBL16257666 1.00 NOD1 (0.65) NOD1GNPATFOLH1RIMKLANAALAD2
SCHEMBL13641019 1.00 NOD1 (0.65) NOD1GNPATFOLH1RIMKLANAALAD2
SCHEMBL18573664 1.00 NOD1 (0.65) NOD1GNPATFOLH1RIMKLANAALAD2
SCHEMBL27322925 1.00 NOD1 (0.65) NOD1GNPATFOLH1RIMKLANAALAD2
SCHEMBL12980909 1.00 NOD1 (0.65) NOD1GNPATFOLH1RIMKLANAALAD2
SCHEMBL18573773 1.00 NOD1 (0.65) NOD1GNPATFOLH1RIMKLANAALAD2
SCHEMBL13974161 1.00 NOD1 (0.65) NOD1GNPATFOLH1RIMKLANAALAD2
SCHEMBL72619 1.00 NOD1 (0.65) NOD1GNPATFOLH1RIMKLANAALAD2
SCHEMBL91076 0.91 NOD1 (0.61) NOD1GNPATFOLH1SLC6A5KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239852-A1 AMYLIN RECEPTOR AGONISTS NOVO NORDISK A/S (DK) 2024-07-18 US disclosed
US-20240239852-A1 AMYLIN RECEPTOR AGONISTS NOVO NORDISK A/S (DK) 2024-07-18 US disclosed
US-9486506-B2 Glucagon analogues NOVO NORDISK A/S (DK) 2016-11-08 US disclosed
US-20150182594-A1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK AS (DK) 2015-07-02 US disclosed
US-8815802-B2 GLP-1 analogues and derivatives NOVO NORDISK A/S (DK) 2014-08-26 US disclosed
US-20140206608-A1 Exendin-4 Derivatives SANOFI (FR) 2014-07-24 US disclosed
US-20130252884-A1 FGF21 ANALOGUES AND DERIVATIVES NOVO NORDISK A/S (DK) 2013-09-26 US disclosed
US-8536122-B2 Acylated GLP-1 compounds NOVO NORDISK A/S (DK) 2013-09-17 US disclosed
US-20130143798-A1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK A/S (DK) 2013-06-06 US disclosed
US-20130143798-A1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK A/S (DK) 2013-06-06 US disclosed
US-20130053311-A1 GLP-1 ANALOGUES AND DERIVATIVES NOVO NORDISK A/S (DK) 2013-02-28 US disclosed
US-20130035285-A1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK A/S (DK) 2013-02-07 US disclosed
US-20130035285-A1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK A/S (DK) 2013-02-07 US disclosed
US-20120295847-A1 Acylated GLP-1 Compounds NOVO NORDISK A/S (DK) 2012-11-22 US disclosed
US-20100305032-A1 Novel GLP-1 Derivatives NOVO NORDISK A/S (DK) 2010-12-02 US disclosed
US-20100305032-A1 Novel GLP-1 Derivatives NOVO NORDISK A/S (DK) 2010-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130143798-A1 NOVEL GLUCAGON ANALOGUES GLP1R, GCG, IAPP NOD1 1083/4885GNPAT 1084/4885FOLH1 251/4885
US-20150182594-A1 NOVEL GLUCAGON ANALOGUES GLP1R, GCG, GCGR NOD1 1939/4885GNPAT 1293/4885FOLH1 352/4885
US-20140206608-A1 Exendin-4 Derivatives GLP1R, MC4R, NPY4R NOD1 2246/4885GNPAT 1055/4885FOLH1 1694/4885
US-20120295847-A1 Acylated GLP-1 Compounds GLP1R, GIPR, GCGR NOD1 1340/4885GNPAT 428/4885FOLH1 450/4885
US-20100305032-A1 Novel GLP-1 Derivatives GLP1R, GIPR, IAPP NOD1 575/4885GNPAT 2070/4885FOLH1 555/4885
US-20130035285-A1 NOVEL GLUCAGON ANALOGUES GLP1R, GIPR, IAPP NOD1 1856/4885GNPAT 1392/4885FOLH1 303/4885
US-20240239852-A1 AMYLIN RECEPTOR AGONISTS GLP1R, GPR119, GIPR NOD1 390/4885GNPAT 2064/4885FOLH1 1914/4885
US-20130252884-A1 FGF21 ANALOGUES AND DERIVATIVES FGFR1, FGF1, FGF23 NOD1 812/4885GNPAT 603/4885FOLH1 973/4885
US-20130053311-A1 GLP-1 ANALOGUES AND DERIVATIVES GLP1R, IAPP, SLC5A1 NOD1 221/4885GNPAT 2389/4885FOLH1 1590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.