Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.39 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.39 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.39 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107760 | 1.00 | KMT2A (0.46) | KMT2ASMN1; SMN2HSD17B10MAPTKDM4E | |
| SCHEMBL9107822 | 0.86 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2HSD17B10MAPTKDM4E | |
| SCHEMBL9107827 | 0.86 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2HSD17B10MAPTKDM4E | |
| SCHEMBL16480424 | 0.78 | ALDH1A1 (0.45) | KMT2ASMN1; SMN2HSD17B10MAPTKDM4E | |
| SCHEMBL21661131 | 0.78 | SMN1; SMN2 (0.38) | KMT2ASMN1; SMN2HSD17B10KEAP1NFE2L2 | |
| SCHEMBL3703692 | 0.76 | CNR1 (0.62) | KMT2ASMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL3698930 | 0.76 | CNR1 (0.62) | KMT2ASMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL31381239 | 0.76 | NEK2 (0.49) | HSD17B10KDM4EHPGDUSP2 | |
| SCHEMBL9891860 | 0.75 | ALDH1A1 (0.42) | KMT2ASMN1; SMN2HSD17B10MAPTKDM4E | |
| SCHEMBL13285331 | 0.75 | ALDH1A1 (0.42) | KMT2ASMN1; SMN2HSD17B10MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | KMT2A 3551/4885SMN1; SMN2 4659/4885HSD17B10 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.