Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAT2A | P31153 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107827 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2AHSD17B10MAPTKDM4E | |
| SCHEMBL9107770 | 0.86 | KMT2A (0.46) | SMN1; SMN2KMT2AHSD17B10MAPTKDM4E | |
| SCHEMBL9107760 | 0.86 | KMT2A (0.46) | SMN1; SMN2KMT2AHSD17B10MAPTKDM4E | |
| SCHEMBL3698930 | 0.83 | CNR1 (0.62) | SMN1; SMN2KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL3703692 | 0.83 | CNR1 (0.62) | SMN1; SMN2KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL3783905 | 0.80 | CNR1 (0.58) | SMN1; SMN2KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29221025 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AHSD17B10ALDH1A1HPGD | |
| SCHEMBL29221023 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AHSD17B10ALDH1A1HPGD | |
| SCHEMBL16480386 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2KMT2AHSD17B10MAPTKDM4E | |
| SCHEMBL9107214 | 0.76 | ADRA1A (0.48) | SMN1; SMN2KMT2AHSD17B10MAPTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | SMN1; SMN2 4659/4885KMT2A 3551/4885HSD17B10 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.