Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.35 |
| ▸ | CA1 | P00915 | 6/20 | 0.35 |
| ▸ | CA2 | P00918 | 6/20 | 0.35 |
| ▸ | CA9 | Q16790 | 6/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2918409 | 1.00 | THRB (0.41) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL2913295 | 1.00 | THRB (0.41) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL2922320 | 0.98 | THRB (0.43) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL27090158 | 0.98 | THRB (0.43) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL8805375 | 0.95 | THRB (0.39) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL28256027 | 0.94 | THRB (0.38) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL26676555 | 0.88 | THRB (0.36) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL28961491 | 0.87 | LPAR3 (0.44) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL2950261 | 0.87 | TSHR (0.40) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL10880322 | 0.87 | LPAR3 (0.44) | THRBMEN1HTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142956-A1 | PROCESS FOR REACTING HYDROXYL COMPOUNDS WITH LINEAR, BRANCHED OR CYCLIC POLYALKYLSILOXANES | EVONIK GOLDSCHMIDT GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142956-A1 | PROCESS FOR REACTING HYDROXYL COMPOUNDS WITH LINEAR, BRANCHED OR CYCLIC POLYALKYLSILOXANES | HAO2, MSR1, OR10J3 | THRB 1552/4885MEN1 2375/4885HTT 1901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.