Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 15/20 | 0.76 |
| ▸ | MAPT | P10636 | 7/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.76 |
| ▸ | NPC1 | O15118 | 4/20 | 0.76 |
| ▸ | RAB9A | P51151 | 4/20 | 0.76 |
| ▸ | GAA | P10253 | 3/20 | 0.76 |
| ▸ | GLA | P06280 | 2/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | SNCA | P37840 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492713 | 0.87 | APP (1.00) | APPMAPTKDM4ENPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL7994519 | 0.86 | APP (0.97) | APPMAPTKDM4ENPC1RAB9A | |
| SCHEMBL2628249 | 0.84 | APP (0.94) | APPMAPTKDM4ENPC1RAB9A | |
| Ethylene SCHEMBL27827468 | 0.83 | APP (0.91) | APPMAPTKDM4ENPC1RAB9A | |
| 1,2-Dichloroethane SCHEMBL2195018 | 0.81 | APP (0.86) | APPMAPTKDM4ENPC1RAB9A | |
| SCHEMBL1984424 | 0.80 | APP (0.84) | APPMAPTKDM4ENPC1RAB9A | |
| SCHEMBL1984426 | 0.80 | APP (0.84) | APPMAPTKDM4ENPC1RAB9A | |
| SCHEMBL12422217 | 0.78 | MAPT (0.81) | APPMAPTKDM4ENPC1RAB9A | |
| Hydrochlorthiazide SCHEMBL4977398 | 0.77 | GAA (0.57) | APPMAPTKDM4ENPC1RAB9A | |
| SCHEMBL3190615 | 0.77 | MAPT (0.69) | APPMAPTKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527186-A4 | — | UNIV ILLINOIS (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0527186-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | The Board of Trustees for the University of Illinois (US) | 1993-02-17 | — | — | EP | disclosed |
| WO-1991016820-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1991-11-14 | — | — | WO | disclosed |