Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 9/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391443 | 0.91 | SMYD3 (0.35) | CETPSMYD3GPR119KCNH2KDM4E | |
| SCHEMBL389991 | 0.89 | GPR119 (0.47) | CETPGPR119 | |
| SCHEMBL1069804 | 0.88 | GPR119 (0.33) | CETPGPR119KDM4EALDH1A1HPGD | |
| SCHEMBL388767 | 0.85 | KCNH2 (0.40) | CETPKCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL391825 | 0.84 | KCNH2 (0.36) | CETPGPR119KCNH2RAB9ANOS3 | |
| SCHEMBL390775 | 0.84 | KCNH2 (0.35) | CETPGPR119KCNH2NOS3NOS1 | |
| SCHEMBL390150 | 0.83 | JAK1 (0.36) | GPR119KCNH2ALDH1A1RAB9A | |
| SCHEMBL389486 | 0.83 | CA2 (0.33) | CETPGPR119KCNH2 | |
| SCHEMBL391559 | 0.82 | JAK1 (0.35) | GPR119KCNH2ALDH1A1 | |
| SCHEMBL391645 | 0.81 | TLR9 (0.35) | GPR119KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193359-B2 | G-protein coupled receptor agonists | PROSIDION LIMITED (GB) | 2012-06-05 | — | — | US | disclosed |