SCHEMBL9107926

SCHEMBL9107926

CC1(C)OCC(OC(=O)c2ccccc2C(=O)Cl)CO1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
CYP3A4 P08684 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45
PTPRF P10586 1/20 0.41
PTPN2 P17706 1/20 0.41
PTPN1 P18031 1/20 0.41
TSHR P16473 2/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP2D6 P10635 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GAA P10253 1/20 0.38
SCN1A P35498 3/20 0.36
SCN2A Q99250 3/20 0.36
SCN3A Q9NY46 3/20 0.36
HTR7 P34969 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9109303 0.75 TMEM97 (0.45) ALDH1A1CYP2C19CYP1A2TSHRPOLB
SCHEMBL7757445 0.74 MEN1 (0.51) ALDH1A1LMNAPTPRFPTPN2PTPN1
SCHEMBL9107126 0.72 TSHR (0.32) TSHRHTR7
SCHEMBL9108416 0.72 TSHR (0.41) ALDH1A1CYP3A4CYP2C19LMNACYP1A2
SCHEMBL16406060 0.69 GAA (0.48) LMNATSHRTDP1GAASCN1A
SCHEMBL24088563 0.69 ALDH1A1 (0.51) ALDH1A1LMNABCHE
SCHEMBL28763010 0.69 PTPRF (0.46) ALDH1A1CYP3A4CYP2C9CYP2C19PTPRF
SCHEMBL3846512 0.69 ALDH1A1 (0.84) ALDH1A1CYP3A4CYP2C9CYP2C19LMNA
SCHEMBL3846508 0.69 ALDH1A1 (0.84) ALDH1A1CYP3A4CYP2C9CYP2C19LMNA
SCHEMBL6908933 0.69 ALDH1A1 (0.84) ALDH1A1CYP3A4CYP2C9CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5451654-A Addition polymerization catalyst ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-09-19 US disclosed
US-5387654-A Hydroxy-peroxides and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-02-07 US disclosed
EP-0381135-B1 Novel hydroxy-peroxides and their uses ATOCHEM NORTH AMERICA (US) 1994-06-01 EP disclosed
US-5304649-A Curing agent for unsaturated polyesters ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-04-19 US disclosed
EP-0381135-A2 Novel hydroxy-peroxides and their uses ATOCHEM NORTH AMERICA, INC. (US) 1990-08-08 EP disclosed