Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422522 | 0.79 | TSHR (0.52) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL19487349 | 0.74 | TSHR (0.64) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL28496837 | 0.74 | TSHR (0.49) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL9109303 | 0.73 | TMEM97 (0.45) | TSHRALDH1A1L3MBTL1MAPK1NPC1 | |
| SCHEMBL23405035 | 0.72 | ADRB2 (0.47) | TSHRALDH1A1L3MBTL1TP53MAPK1 | |
| SCHEMBL9107926 | 0.72 | ALDH1A1 (0.45) | TSHRALDH1A1TDP1CYP3A4LMNA | |
| SCHEMBL19601053 | 0.71 | TSHR (0.67) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL3360968 | 0.71 | TSHR (0.81) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL31663503 | 0.70 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL15274672 | 0.69 | LMNA (0.46) | TSHRALDH1A1TDP1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451654-A | Addition polymerization catalyst | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-09-19 | — | — | US | disclosed |
| US-5387654-A | Hydroxy-peroxides and their uses | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0381135-B1 | Novel hydroxy-peroxides and their uses | ATOCHEM NORTH AMERICA (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5304649-A | Curing agent for unsaturated polyesters | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-04-19 | — | — | US | disclosed |