Imidazole

Imidazole

SCHEMBL9107976

N#Cc1nc[nH]c1C#N.N#Cc1nc[nH]c1C#N.c1c[nH]cn1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
FKBP5 Q13451 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL21518188 0.79 NEK2 (0.34)
Imidazole SCHEMBL28201690 0.70
SCHEMBL9697260 0.70
SCHEMBL16887856 0.70
Imidazole SCHEMBL504307 0.69
Imidazole SCHEMBL28192741 0.69 ALDH1A1 (0.93) ALDH1A1FKBP5
Imidazole SCHEMBL876245 0.69 ALDH1A1 (0.93) ALDH1A1FKBP5
Imidazole SCHEMBL8815117 0.69 ALDH1A1 (0.93) ALDH1A1FKBP5
Imidazole SCHEMBL8815120 0.69
Imidazole SCHEMBL9341261 0.68 ALDH1A1 (0.68) ALDH1A1FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0527186-A4 UNIV ILLINOIS (US) 1995-01-18 EP disclosed
EP-0527186-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS The Board of Trustees for the University of Illinois (US) 1993-02-17 EP disclosed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO disclosed