Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL504307 | 1.00 | — | — | |
| Imidazole SCHEMBL8815120 | 1.00 | — | — | |
| Imidazole SCHEMBL28192741 | 1.00 | ALDH1A1 (0.93) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL8815117 | 1.00 | ALDH1A1 (0.93) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL23140246 | 0.97 | — | — | |
| Imidazole SCHEMBL15813745 | 0.97 | — | — | |
| Imidazole SCHEMBL28638683 | 0.97 | — | — | |
| Imidazole SCHEMBL28066335 | 0.97 | — | — | |
| Imidazole SCHEMBL11528204 | 0.97 | — | — | |
| Imidazole SCHEMBL29282555 | 0.97 | ALDH1A1 (0.87) | ALDH1A1FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240964-A | Adding piperazine catalyst with imidazole, triazine or amidine compound to create difference in gas evolution between inner and outer parts of plastic liquid | TOKYO SEAT CO., LTD. (JP) | 1993-08-31 | — | — | US | claimed |
| EP-0358377-B1 | BIS IMIDAZOLE ETHERS AS METAL DEACTIVATORS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1993-04-28 | — | — | EP | claimed |
| US-5141684-A | Using catalyst which creates difference in gas evolution between inner and outer parts of plastic liquid in mold to form high density layer on outer surface | TOKYO SHEET CO., LTD. (JP) | 1992-08-25 | — | — | US | claimed |
| US-5139713-A | One step molding, high density surfaces | TOKYO SHEET CO., LTD. (JP) | 1992-08-18 | — | — | US | claimed |
| US-5011935-A | Imidazole ether compounds | SAN-APRO LIMITED (JP) | 1991-04-30 | — | — | US | claimed |
| EP-0358377-A1 | Bis imidazole ethers as metal deactivators | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1990-03-14 | — | — | EP | claimed |
| US-4869838-A | LUBRICANTS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1989-09-26 | — | — | US | claimed |
| JP-4298519-A | — | — | None | — | — | JP | disclosed |
| JP-3033120-A | — | — | None | — | — | JP | disclosed |
| JP-2117665-A | — | — | None | — | — | JP | disclosed |
| JP-2160768-A | — | — | None | — | — | JP | disclosed |
| EP-3484982-B1 | POLYESTER DISPERSANTS, SYNTHESIS AND USE THEREOF | CHEVRON ORONITE CO (US) | 2024-05-22 | — | — | EP | disclosed |
| EP-3484982-A2 | POLYESTER DISPERSANTS, SYNTHESIS AND USE THEREOF | Chevron Oronite Company LLC (US) | 2019-05-22 | — | — | EP | disclosed |
| US-4869838-A | LUBRICANTS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1989-09-26 | — | — | US | disclosed |
| EP-0156508-B1 | ANTIFUNGAL AEROSOL SOLUTION | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-06-28 | — | — | EP | disclosed |
| EP-0156507-A1 | Antifungal dermatological solution | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-10-02 | — | — | EP | disclosed |
| EP-0156508-A1 | Antifungal aerosol solution | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-10-02 | — | — | EP | disclosed |
| US-4224452-A | HYDROLYSIS | ETHYL CORPORATION (US) | 1980-09-23 | — | — | US | disclosed |
| US-4224452-A | HYDROLYSIS | ETHYL CORPORATION (US) | 1980-09-23 | — | — | US | disclosed |
| JP-H00333120-A | — | — | 0001-01-01 | — | — | JP | disclosed |