Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3607570 | 0.90 | HTT (0.52) | HTTPOLBCYP3A4TSHRALDH1A1 | |
| SCHEMBL5163677 | 0.84 | ALDH1A1 (0.50) | HTTPOLBCYP3A4TSHRALDH1A1 | |
| SCHEMBL1645387 | 0.79 | ALDH1A1 (0.58) | HTTCYP3A4TSHRALDH1A1TDP1 | |
| SCHEMBL2354936 | 0.78 | ALDH1A1 (0.62) | HTTPOLBCYP3A4TSHRALDH1A1 | |
| SCHEMBL433268 | 0.78 | CYP3A4 (0.59) | HTTPOLBCYP3A4TSHRALDH1A1 | |
| SCHEMBL14369940 | 0.76 | TSHR (0.52) | HTTPOLBCYP3A4TSHRALDH1A1 | |
| SCHEMBL10586724 | 0.75 | GPR35 (0.42) | HTTPOLBCYP3A4TSHRALDH1A1 | |
| SCHEMBL2119829 | 0.75 | ALDH1A1 (0.62) | HTTPOLBCYP3A4TSHRALDH1A1 | |
| SCHEMBL7928377 | 0.75 | TSHR (0.45) | HTTPOLBTSHRALDH1A1GPR35 | |
| SCHEMBL6978784 | 0.75 | MEN1 (0.55) | HTTTSHRALDH1A1GPR35TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120141398-A1 | HAIR DYE CONTAINING ONE OR MORE EDIBLE OR COSMETIC COLORS | CHUANG KUO SHENG (TW) | 2012-06-07 | — | — | US | disclosed |