Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | IDO1 | P14902 | 4/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.50 |
| ▸ | RAF1 | P04049 | 2/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224770 | 0.84 | KDM4E (1.00) | CYP3A4KDM4EMAPTIDO1MAPK14 | |
| SCHEMBL1387736 | 0.83 | KDM4E (0.81) | CYP3A4KDM4EMAPTIDO1MAPK14 | |
| SCHEMBL4882839 | 0.83 | KDM4E (0.81) | CYP3A4KDM4EMAPTIDO1MAPK14 | |
| Bromide SCHEMBL31020961 | 0.82 | KDM4E (0.96) | CYP3A4KDM4EMAPTIDO1MAPK14 | |
| Imidazole SCHEMBL8030609 | 0.81 | MAPK14 (0.48) | CYP3A4KDM4EMAPTIDO1MAPK14 | |
| Biphenyl SCHEMBL27756385 | 0.78 | ALDH1A1 (0.62) | CYP3A4KDM4EMAPTIDO1ALDH1A1 | |
| Biphenyl SCHEMBL986473 | 0.78 | ALDH1A1 (0.62) | CYP3A4KDM4EMAPTIDO1ALDH1A1 | |
| 2-Phenylimidazole SCHEMBL9568277 | 0.77 | KDM4E (0.71) | CYP3A4KDM4EMAPTIDO1MAPK14 | |
| Biphenyl SCHEMBL28667880 | 0.77 | ALDH1A1 (0.59) | CYP3A4KDM4EMAPTIDO1MAPK14 | |
| Biphenyl SCHEMBL28151555 | 0.77 | ALDH1A1 (0.59) | CYP3A4KDM4EMAPTIDO1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527186-A4 | — | UNIV ILLINOIS (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0527186-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | The Board of Trustees for the University of Illinois (US) | 1993-02-17 | — | — | EP | disclosed |
| WO-1991016820-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1991-11-14 | — | — | WO | disclosed |