Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL920685 | 0.81 | KDM4E (0.37) | MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL920804 | 0.80 | ALDH1A1 (0.45) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL920237 | 0.79 | ALDH1A1 (0.41) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL919478 | 0.78 | AOC3 (0.38) | — | |
| SCHEMBL920385 | 0.78 | AOC3 (0.38) | — | |
| SCHEMBL919477 | 0.78 | AOC3 (0.38) | — | |
| SCHEMBL920386 | 0.78 | AOC3 (0.38) | — | |
| SCHEMBL920411 | 0.78 | ALDH1A1 (0.40) | MEN1KMT2ASMN1; SMN2HPGDTSHR | |
| SCHEMBL3844869 | 0.77 | MAPT (0.42) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| Water SCHEMBL1169336 | 0.77 | AOC3 (0.52) | MEN1LMNAMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033139-B | Heteroaryl piperidine and heteroaryl based piperazine derivative as fungicide | 拜耳知识产权有限责任公司 | 2019-11-19 | — | — | CN | claimed |
| US-9975889-B2 | Heteroaryl piperidine and heteroaryl piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-05-22 | — | — | US | claimed |
| US-9914728-B2 | Heteroaryl piperidine and heteroaryl piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-03-13 | — | — | US | claimed |
| CN-107033139-A | It is used as the heteroaryl piperidine and heteroaryl based piperazine derivative of fungicide | 拜耳知识产权有限责任公司 | 2017-08-11 | — | — | CN | claimed |
| US-20170044154-A1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | US | claimed |
| US-20170044153-A1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH | 2017-02-16 | — | — | US | claimed |
| US-7041388-B1 | Substituted poly(arylene vinylenes), process for their preparation and their use in electroluminescent devices | SEMICONDUCTORS GMBH (DE) | 2006-05-09 | — | — | US | claimed |
| EP-0831812-B1 | METHODS AND COMPOSITIONS FOR STIMULATING NEURITE GROWTH | VERTEX PHARMA (US) | 2005-12-07 | — | — | EP | claimed |
| CN-1170813-C | N2 phenylamidine derivatives | �ݶ�ũ������˾ | 2004-10-13 | — | — | CN | claimed |
| US-6407100-B1 | HORTICULTURE, AGRICULTURE, WOOD PRESERVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-18 | — | — | US | claimed |
| US-5620971-A | Biologically active acylated amino acid derivatives | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1997-04-15 | — | — | US | claimed |
| EP-0621864-B1 | 2-(2-BENZO(b)THIENYL)-3-METHOXYACRYLATE AND -2-IMINOACETATE DERIVATIVES TO BE USED AS PESTICIDES | CIBA GEIGY AG (CH) | 1996-12-27 | — | — | EP | claimed |
| WO-1996006072-A1 | OXIME ETHERS AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1996-02-29 | — | — | WO | claimed |
| EP-0651737-A1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES | Novartis AG (CH) | 1995-05-10 | — | — | EP | claimed |
| WO-1994026700-A1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1994-11-24 | — | — | WO | claimed |
| EP-0621864-A1 | 2-(2-BENZO(b)THIENYL)-3-METHOXYACRYLATE AND -2-IMINOACETATE DERIVATIVES TO BE USED AS PESTICIDES. | CIBA GEIGY AG (CH) | 1994-11-02 | — | — | EP | claimed |
| EP-0584223-A1 | NOVEL IMMUNOSUPPRESSIVE COMPOUNDS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1994-03-02 | — | — | EP | claimed |
| WO-1993008183-A1 | 2-(2-BENZO(b)THIENYL)-3-METHOXYACRYLATE AND -2-IMINOACETATE DERIVATIVES TO BE USED AS PESTICIDES | CIBA-GEIGY AG (CH) | 1993-04-29 | — | — | WO | claimed |
| WO-1992019593-A1 | NOVEL IMMUNOSUPPRESSIVE COMPOUNDS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1992-11-12 | — | — | WO | claimed |
| US-3935250-A | PESTICIDE | CIBA-GEIGY CORPORATION (US) | 1976-01-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044154-A1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | PRXL2A, CYP1A1, CAT | MEN1 2086/4885LMNA 2351/4885MAPT 3867/4885 |
| US-20170044153-A1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | PRXL2A, CYP1A1, CAT | MEN1 2086/4885LMNA 2351/4885MAPT 3867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.