Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9108518 | 1.00 | GSK3B (0.49) | GSK3BTNKS2CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL9109613 | 1.00 | GSK3B (0.49) | GSK3BTNKS2CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL2361451 | 0.78 | KDM4E (0.57) | TNKS2CYP1A2SMN1; SMN2KDM4EMAPT | |
| SCHEMBL9109997 | 0.76 | NOS1 (0.38) | KDM4EMAPTKMT2AMEN1HTT | |
| SCHEMBL14765037 | 0.76 | GSK3B (0.76) | GSK3BTNKS2CYP1A2SMN1; SMN2MAPT | |
| SCHEMBL31477093 | 0.73 | GSK3B (0.43) | GSK3BTNKS2CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL31477058 | 0.73 | GSK3B (0.43) | GSK3BTNKS2CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL31477218 | 0.73 | GSK3B (0.43) | GSK3BTNKS2CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL31477191 | 0.73 | GSK3B (0.43) | GSK3BTNKS2CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL31477285 | 0.73 | GSK3B (0.43) | GSK3BTNKS2CYP1A2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424311-A | A viricides for treating viral diseases; HIV enzyme inhibitor | HOESCHST AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |