Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109613 | 0.76 | GSK3B (0.49) | NOS1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL9108518 | 0.76 | GSK3B (0.49) | NOS1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL9109620 | 0.76 | GSK3B (0.49) | NOS1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL8316117 | 0.75 | XIAP (0.50) | KMT2AMEN1POLBBRPF1CREBBP | |
| SCHEMBL10273855 | 0.74 | ALDH1A1 (0.44) | MAPTKMT2AKDM4EALDH1A1GAA | |
| SCHEMBL2361451 | 0.72 | KDM4E (0.57) | MAPTKMT2AKDM4EALDH1A1GAA | |
| SCHEMBL28380362 | 0.71 | ALDH1A1 (0.42) | MAPTKMT2AKDM4EALDH1A1GAA | |
| SCHEMBL16754393 | 0.71 | ALDH1A1 (0.42) | MAPTKMT2AKDM4EALDH1A1GAA | |
| SCHEMBL28381212 | 0.71 | ALDH1A1 (0.42) | MAPTKMT2AKDM4EALDH1A1GAA | |
| SCHEMBL19736194 | 0.70 | XIAP (0.33) | MAPTKMT2AKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424311-A | A viricides for treating viral diseases; HIV enzyme inhibitor | HOESCHST AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |
| EP-0590428-A1 | Azaquinoxalines, process for their preparation, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |