Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9110424 | 0.77 | MEN1 (0.38) | PGRKMT2AMGAT2 | |
| SCHEMBL21491516 | 0.75 | JUN (0.35) | — | |
| SCHEMBL14773426 | 0.74 | RAD52 (0.39) | — | |
| SCHEMBL25348731 | 0.73 | PGR (0.42) | PGRKMT2APDK2PDK4 | |
| SCHEMBL30540460 | 0.73 | PGR (0.42) | PGRKMT2APDK2PDK4 | |
| SCHEMBL15578826 | 0.68 | MARK3 (0.43) | PGRPDK2PDK4 | |
| SCHEMBL9076137 | 0.68 | CHEK1 (0.44) | PGR | |
| SCHEMBL8316117 | 0.68 | XIAP (0.50) | PGRKMT2A | |
| SCHEMBL31368886 | 0.68 | PGR (0.35) | PGRKMT2AMGAT2PDK2PDK4 | |
| SCHEMBL16563723 | 0.67 | XIAP (0.47) | PGRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424311-A | A viricides for treating viral diseases; HIV enzyme inhibitor | HOESCHST AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |
| EP-0590428-A1 | Azaquinoxalines, process for their preparation, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |