Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | LYN | P07948 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrimethanil SCHEMBL20817 | 0.91 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTTAAR1RAB9ANPC1 | |
| Pyrimethanil SCHEMBL22041985 | 0.89 | SMN1; SMN2 (0.69) | SMN1; SMN2HTTTAAR1RAB9ANPC1 | |
| Pyrimethanil SCHEMBL10664468 | 0.89 | SMN1; SMN2 (0.69) | SMN1; SMN2HTTTAAR1RAB9ANPC1 | |
| Mepanipyrim SCHEMBL26109940 | 0.84 | TAAR1 (0.49) | SMN1; SMN2HTTTAAR1KCNH2RAB9A | |
| Cyprodinil SCHEMBL9283286 | 0.84 | TAAR1 (0.49) | SMN1; SMN2HTTTAAR1KCNH2RAB9A | |
| SCHEMBL15968669 | 0.82 | AURKA (0.63) | RAB9ANPC1MAPTMAPK1CHEK1 | |
| SCHEMBL911 | 0.82 | AURKA (0.63) | RAB9ANPC1MAPTMAPK1CHEK1 | |
| SCHEMBL4624975 | 0.81 | NPC1 (0.65) | SMN1; SMN2TAAR1RAB9ANPC1MAPT | |
| Pyrimethanil SCHEMBL28273473 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2HTTTAAR1RAB9ANPC1 | |
| SCHEMBL6370265 | 0.80 | AURKA (0.61) | RAB9ANPC1MAPTMAPK1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242365-B1 | COMBINATIONS OF PYRIMETHANIL AND PYRION COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2013-01-16 | — | — | EP | claimed |
| EP-2579718-B1 | COMBINATIONS OF PYRIMETHANIL AND MONOTERPENES | JANSSEN PHARMACEUTICA NV (BE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2319321-A1 | Use of fungicidal combinations of active compounds | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| US-20110071177-A1 | FUNGICIDAL ACTIVE SUBSTANCE COMBINATION | BAYER CROPSCIENCE AG (DE) | 2011-03-24 | — | — | US | disclosed |
| US-20090170884-A1 | FUNGICIDAL ACTIVE SUBSTANCE COMBINATION | BAYER CROPSCIENCE AG (DE) | 2009-07-02 | — | — | US | disclosed |
| US-20090069356-A1 | USE OF ANILINOPYRIMIDINES IN WOOD PROTECTION | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-12 | — | — | US | disclosed |
| US-20090069356-A1 | USE OF ANILINOPYRIMIDINES IN WOOD PROTECTION | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-12 | — | — | US | disclosed |
| EP-1959741-A2 | FUNGICIDAL ACTIVE SUBSTANCE COMBINATION | Bayer CropScience AG (DE) | 2008-08-27 | — | — | EP | disclosed |
| CN-101043988-A | Use of anilinopyrimidines in wood protection | JANSSEN PHARMACEUTICA NV (BE) | 2007-09-26 | — | — | CN | disclosed |
| EP-1827782-A1 | USE OF ANILINOPYRIMIDINES IN WOOD PROTECTION | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-09-05 | — | — | EP | disclosed |
| EP-1827782-A1 | USE OF ANILINOPYRIMIDINES IN WOOD PROTECTION | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2007065576-A2 | FUNGICIDAL ACTIVE SUBSTANCE COMBINATION | BAYER CROPSCIENCE AG (DE) | 2007-06-14 | — | — | WO | disclosed |
| WO-2006045751-A1 | USE OF ANILINOPYRIMIDINES IN WOOD PROTECTION | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-04 | — | — | WO | disclosed |
| WO-2006045751-A1 | USE OF ANILINOPYRIMIDINES IN WOOD PROTECTION | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071177-A1 | FUNGICIDAL ACTIVE SUBSTANCE COMBINATION | GABBR1, TH, PFAS | SMN1; SMN2 3013/4885HTT 2819/4885TAAR1 1342/4885 |
| US-20090069356-A1 | USE OF ANILINOPYRIMIDINES IN WOOD PROTECTION | DPYD, DPM1, QDPR | SMN1; SMN2 3216/4885HTT 3591/4885TAAR1 4352/4885 |
| US-20090170884-A1 | FUNGICIDAL ACTIVE SUBSTANCE COMBINATION | CYP3A7, CYP4X1, CYP1A2 | SMN1; SMN2 1741/4885HTT 4738/4885TAAR1 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.