Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LIG1 | P18858 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 10/20 | 0.41 |
| ▸ | CASP3 | P42574 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625089 | 0.87 | CES1 (0.55) | CES1MAOAMAOBLIG1TGM2 | |
| SCHEMBL5893941 | 0.85 | CES1 (0.53) | CES1MAOAMAOBLIG1TGM2 | |
| SCHEMBL3737913 | 0.81 | GSK3B (0.49) | CES1TGM2CASP3MEN1POLB | |
| SCHEMBL6658776 | 0.73 | AURKA (0.53) | CES1TGM2MAPT | |
| SCHEMBL2838571 | 0.72 | CES1 (0.60) | CES1MAOAMAOBTGM2CASP3 | |
| SCHEMBL5975593 | 0.72 | CES1 (0.60) | CES1MAOAMAOBTGM2MEN1 | |
| SCHEMBL281203 | 0.72 | CES1 (0.60) | CES1MAOAMAOBTGM2MEN1 | |
| SCHEMBL30716604 | 0.72 | CES1 (1.00) | CES1MAOAMAOBTGM2 | |
| SCHEMBL2136384 | 0.72 | CES1 (0.60) | CES1MAOAMAOBPOLB | |
| SCHEMBL4242823 | 0.72 | CES1 (0.60) | CES1MAOAMAOBTGM2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995009193-A1 | POLYMERS FORMED FROM BIS (2,3-DIHYDROINDOLE-2,3-DIONE) COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1995-04-06 | — | — | WO | disclosed |