Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 2/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11921526 | 0.83 | CES1 (0.41) | CES1MAOAMAOBTGM2RET | |
| SCHEMBL31107461 | 0.80 | CES1 (0.43) | CES1MAOAMAOBTGM2RET | |
| SCHEMBL30835279 | 0.75 | CES1 (0.60) | CES1MAOAMAOBTGM2RET | |
| SCHEMBL5975593 | 0.75 | CES1 (0.60) | CES1MAOAMAOBTGM2RET | |
| SCHEMBL30716604 | 0.75 | CES1 (1.00) | CES1MAOAMAOBTGM2PBRM1 | |
| SCHEMBL4242823 | 0.75 | CES1 (0.60) | CES1MAOAMAOBTGM2PBRM1 | |
| SCHEMBL282066 | 0.75 | CES1 (1.00) | CES1MAOAMAOBTGM2PBRM1 | |
| SCHEMBL2136384 | 0.75 | CES1 (0.60) | CES1MAOAMAOBRETPBRM1 | |
| SCHEMBL2838571 | 0.75 | CES1 (0.60) | CES1MAOAMAOBTGM2RET | |
| SCHEMBL31728330 | 0.73 | CES1 (0.48) | CES1MAOAMAOBTGM2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215782-B | Preparation method of 4-bromoindole | 常州琦诺生物科技有限公司 | 2024-09-03 | — | — | CN | claimed |
| CN-114950159-B | Preparation method of aromatic polymer separation membrane based on super acid catalysis | 南京工业大学 | 2023-06-06 | — | — | CN | claimed |
| CN-116217460-A | Preparation and application of indoline-2-one compound derivative | 合肥工业大学 | 2023-06-06 | — | — | CN | claimed |
| CN-115215782-A | Preparation method of 4-bromoindole | 常州琦诺生物科技有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-114950159-A | Preparation method of aromatic polymer separation membrane based on super-acid catalysis preparation | 南京工业大学 | 2022-08-30 | — | — | CN | claimed |
| CN-113912609-A | Preparation method of natural alkaloid tryptanthrin and derivative thereof | 江苏大学 | 2022-01-11 | — | — | CN | claimed |
| CN-111574426-A | Diamine monomer containing isoindigo structure and black polyimide synthesized from diamine monomer | 湘潭大学 | 2020-08-25 | — | — | CN | claimed |
| CN-105693717-A | Preparation method of pyrrolo[4,3,2-de]quinoline | 中国药科大学 | 2016-06-22 | — | — | CN | claimed |
| CN-103554117-B | A kind of preparation method of chiral spiro naphthoquinone benzopyran hydroxyindole compound | ZHANGJIAGANG INSTITUTE OF INDUSTRIAL TECHNOLOGIES SOOCHOW UNIVERSITY (CN) | 2015-09-23 | — | — | CN | claimed |
| CN-102351777-B | Preparation method for chiral 3-hydroxyl-3-methylene nitro indole-2-ketone derivative | UNIV SOOCHOW | 2014-03-19 | — | — | CN | claimed |
| CN-103554117-A | Preparation method of chiral spiro naphthoquinone benzopyran hydroxyindole compound | ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV | 2014-02-05 | — | — | CN | claimed |
| CN-102690226-A | Multi-nitrogen substituted isatin derivative and synthetic method of multi-nitrogen substituted isatin derivative | UNIV GUANGDONG TECHNOLOGY | 2012-09-26 | — | — | CN | claimed |
| CN-102351777-A | Preparation method for chiral 3-hydroxyl-3-methylene nitro indole-2-ketone derivative | UNIV SOOCHOW | 2012-02-15 | — | — | CN | claimed |
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | L'OREAL S.A. | 2007-06-14 | — | — | US | claimed |
| US-7204857-B1 | Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL S.A. (FR) | 2007-04-17 | — | — | US | claimed |
| US-6635090-B1 | Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL, S.A. (FR) | 2003-10-21 | — | — | US | claimed |
| US-6458168-B1 | Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative | L'OREAL S.A. (FR) | 2002-10-01 | — | — | US | claimed |
| US-6451067-B1 | HAIR DYE MIXTURE | L'OREAL S.A. (FR) | 2002-09-17 | — | — | US | claimed |
| CN-122094937-A | Cannabinoid compounds and uses thereof | — | 2026-05-26 | — | — | CN | disclosed |
| EP-0002624-A1 | 2-Benzazepine compounds, processes for their preparation and pharmaceutical compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | KRT18, NDUFB5, NDUFB7 | CES1 3158/4885MAOA 467/4885MAOB 514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.