Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | AOC2 | O75106 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9110764 | 1.00 | TAAR1 (0.46) | TAAR1MAOBIDO1AGXTAOC3 | |
| SCHEMBL1046175 | 0.84 | TAAR1 (0.41) | TAAR1 | |
| SCHEMBL1046173 | 0.84 | TAAR1 (0.41) | TAAR1 | |
| SCHEMBL2098742 | 0.78 | TAAR1 (0.46) | TAAR1MAOBIDO1AGXTAOC3 | |
| SCHEMBL2098744 | 0.78 | TAAR1 (0.46) | TAAR1MAOBIDO1AGXTAOC3 | |
| SCHEMBL3038309 | 0.77 | GPR52 (0.50) | TAAR1MAOBLOXL2 | |
| SCHEMBL3038310 | 0.77 | GPR52 (0.50) | TAAR1MAOBLOXL2 | |
| SCHEMBL7563217 | 0.77 | TAAR1 (0.50) | TAAR1MAOBIDO1AGXTAOC3 | |
| SCHEMBL8995829 | 0.77 | TRPA1 (0.44) | TAAR1MAOBIDO1AGXTLOXL2 | |
| SCHEMBL8995827 | 0.77 | TRPA1 (0.44) | TAAR1MAOBIDO1AGXTLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |