Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401577 | 0.82 | SMN1; SMN2 (0.69) | LMNASMN1; SMN2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL9188247 | 0.77 | SMN1; SMN2 (0.82) | LMNASMN1; SMN2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL9187854 | 0.76 | SMN1; SMN2 (0.80) | LMNASMN1; SMN2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL8947992 | 0.75 | SMN1; SMN2 (0.71) | LMNASMN1; SMN2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL8947996 | 0.75 | SMN1; SMN2 (0.75) | LMNASMN1; SMN2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL29659899 | 0.74 | MEN1 (0.64) | LMNASMN1; SMN2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL22262397 | 0.74 | MEN1 (0.64) | LMNASMN1; SMN2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL11728362 | 0.74 | SMN1; SMN2 (0.82) | LMNASMN1; SMN2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL9188447 | 0.73 | LMNA (0.60) | LMNASMN1; SMN2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL23705539 | 0.73 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2ALDH1A1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453509-A | Functionalization of acyl pyridinium salts | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1995-09-26 | — | — | US | disclosed |
| WO-1995010505-A1 | FUNCTIONALIZATION OF ACYL PYRIDINIUM SALTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1995-04-20 | — | — | WO | disclosed |