Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | AHCY | P23526 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14047302 | 0.91 | FDPS (0.45) | FDPSP2RX7AHCYADORA2AHDAC6 | |
| SCHEMBL14472999 | 0.85 | AHCY (0.60) | AHCYADORA2AADORA1ALDH1A1 | |
| SCHEMBL10284145 | 0.85 | AHCY (0.60) | AHCYADORA2AADORA1ALDH1A1 | |
| SCHEMBL14139510 | 0.77 | AHCY (0.56) | AHCYADORA2AADORA1ALDH1A1 | |
| SCHEMBL13107415 | 0.75 | FDPS (0.47) | FDPSAHCYADORA2AHDAC6MEN1 | |
| SCHEMBL17425126 | 0.75 | HPRT1 (0.53) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL91115 | 0.75 | CDK1 (0.55) | ADORA2AADORA1KMT2ASMN1; SMN2 | |
| SCHEMBL10563489 | 0.74 | FDPS (0.50) | FDPSP2RX7ADORA2AHDAC6FGFR1 | |
| SCHEMBL14472882 | 0.74 | AHCY (0.56) | AHCYADORA2AADORA1ALDH1A1CYP3A4 | |
| SCHEMBL23323404 | 0.74 | FDPS (0.63) | FDPSP2RX7AHCYADORA2AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129357-B2 | N6-(4-hydroxybenzyl)adenosine; Gastrodia extract; neurodegenerative Huntington's disease; trinucleotide repeat disease; hypoglycemic; neurological antiinflammatory; amination of 6-chloropurine ribonucleoside with 4-hydroxybenzylamine; condensation of adenosine with 4-methoxybenzoyl chloride | ACADEMIA SINICA (TW) | 2012-03-06 | — | — | US | disclosed |
| US-20080176816-A1 | Method of making and using an adenosine analogue | ACADEMIA SINICA | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176816-A1 | Method of making and using an adenosine analogue | HTT, ADA, GDA | FDPS 1450/4885P2RX7 743/4885AHCY 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.