Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21585500 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TSHRLSS | |
| SCHEMBL21585499 | 0.97 | TSHR (0.33) | ALDH1A1TSHRLSS | |
| SCHEMBL7194948 | 0.97 | TSHR (0.33) | ALDH1A1TSHRLSS | |
| SCHEMBL9112975 | 0.97 | TSHR (0.33) | ALDH1A1TSHRLSS | |
| SCHEMBL19974063 | 0.97 | TSHR (0.33) | ALDH1A1TSHRLSS | |
| SCHEMBL9110796 | 0.95 | — | — | |
| SCHEMBL5555328 | 0.88 | TSHR (0.39) | ALDH1A1TSHR | |
| SCHEMBL8621883 | 0.88 | TSHR (0.39) | ALDH1A1TSHR | |
| SCHEMBL10918903 | 0.86 | TSHR (0.35) | ALDH1A1TSHR | |
| SCHEMBL10918906 | 0.86 | TSHR (0.35) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |