Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 2/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194948 | 1.00 | TSHR (0.33) | TSHRFASNALDH1A1LSSSOAT1 | |
| SCHEMBL21585499 | 1.00 | TSHR (0.33) | TSHRFASNALDH1A1LSSSOAT1 | |
| SCHEMBL19974063 | 1.00 | TSHR (0.33) | TSHRFASNALDH1A1LSSSOAT1 | |
| SCHEMBL21585500 | 0.97 | ALDH1A1 (0.33) | TSHRALDH1A1LSS | |
| SCHEMBL9111253 | 0.97 | ALDH1A1 (0.33) | TSHRALDH1A1LSS | |
| SCHEMBL9110796 | 0.92 | — | — | |
| SCHEMBL5555328 | 0.91 | TSHR (0.39) | TSHRFASNALDH1A1SOAT1 | |
| SCHEMBL8621883 | 0.91 | TSHR (0.39) | TSHRFASNALDH1A1SOAT1 | |
| SCHEMBL11567093 | 0.87 | TSHR (0.35) | TSHRFASNALDH1A1FAAHTRPV1 | |
| SCHEMBL25178879 | 0.85 | SOAT1 (0.38) | TSHRFASNALDH1A1LSSSOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |