Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10952623 | 0.83 | FFAR1 (0.49) | CYP4F2CYP4A11CA2FFAR1FFAR4 | |
| SCHEMBL7471913 | 0.81 | ALDH1A1 (0.52) | CA2CA1POLBTDP1CA12 | |
| SCHEMBL22223520 | 0.80 | CA2 (0.52) | CYP4F2CYP4A11CA2CA1FFAR1 | |
| SCHEMBL7103590 | 0.78 | CYP4F2 (0.64) | CYP4F2CYP4A11CA2CA1POLB | |
| SCHEMBL2942940 | 0.77 | CYP4F2 (0.41) | CYP4F2CYP4A11CA2CA1HRH3 | |
| SCHEMBL6170098 | 0.77 | CA12 (0.59) | CYP4F2CYP4A11CA2CA1POLB | |
| SCHEMBL6629816 | 0.77 | SMN1; SMN2 (0.57) | CYP4F2CYP4A11CA2CA1POLB | |
| SCHEMBL11983728 | 0.76 | POLB (0.71) | CYP4F2CYP4A11CA2CA1POLB | |
| SCHEMBL11193647 | 0.76 | TDP1 (0.39) | CA2CA1POLBHRH3FFAR1 | |
| SCHEMBL9419326 | 0.76 | MAPT (0.54) | CA2CA1POLBFFAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |