Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.58 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.58 |
| ▸ | LPL | P06858 | 2/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13703310 | 0.98 | CYP4F2 (0.57) | CYP4F2CYP4A11LPLLIPGBCHE | |
| SCHEMBL80185 | 0.94 | CYP4A11 (0.58) | CYP4F2CYP4A11LPLLIPGNOS1 | |
| SCHEMBL238401 | 0.89 | CYP4F2 (0.58) | CYP4F2CYP4A11LPLLIPGBCHE | |
| SCHEMBL10235637 | 0.88 | LPL (0.56) | CYP4F2CYP4A11LPLLIPGPPARG | |
| SCHEMBL2176833 | 0.87 | CYP4F2 (0.56) | CYP4F2CYP4A11LPLLIPGBCHE | |
| SCHEMBL10235642 | 0.86 | LPL (0.57) | CYP4F2CYP4A11LPLLIPGBCHE | |
| SCHEMBL10235701 | 0.86 | LPL (0.57) | CYP4F2CYP4A11LPLLIPGBCHE | |
| SCHEMBL3033916 | 0.86 | LPL (0.62) | CYP4F2CYP4A11LPLLIPGPPARG | |
| SCHEMBL1247008 | 0.85 | CYP4F2 (0.55) | CYP4F2CYP4A11 | |
| SCHEMBL2461558 | 0.83 | LPL (0.59) | LPLLIPGPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |