Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9111866 | 1.00 | CES2 (0.55) | CES2ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL19592309 | 0.85 | CES2 (0.58) | CES2ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL20806278 | 0.84 | CES2 (0.56) | CES2ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL30106109 | 0.79 | CES2 (0.60) | CES2ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL32016 | 0.79 | CES2 (0.60) | CES2ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL14604998 | 0.79 | CES2 (0.51) | CES2ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL28108408 | 0.79 | CES2 (0.56) | CES2ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7447900 | 0.79 | CES2 (0.64) | CES2ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL16957410 | 0.79 | CES2 (0.55) | CES2ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL624734 | 0.78 | CES2 (0.50) | CES2ALDH1A1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |