Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30106109 | 1.00 | CES2 (0.60) | CES2MEN1KMT2ANPSR1GAA | |
| SCHEMBL20219995 | 0.86 | L3MBTL1 (0.48) | CES2ALDH1A1LMNA | |
| SCHEMBL7447900 | 0.83 | CES2 (0.64) | CES2MEN1KMT2ANPSR1GAA | |
| SCHEMBL8865659 | 0.83 | CES2 (0.64) | CES2MEN1KMT2ANPSR1SRD5A2 | |
| SCHEMBL15582371 | 0.83 | HTT (0.45) | CES2ALDH1A1POLBLMNA | |
| SCHEMBL1304921 | 0.82 | L3MBTL1 (0.48) | ALDH1A1POLBLMNA | |
| SCHEMBL24249964 | 0.82 | L3MBTL1 (0.42) | CES2MEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL19710741 | 0.82 | CES2 (0.62) | CES2MEN1KMT2ANPSR1GAA | |
| SCHEMBL23590445 | 0.82 | NPSR1 (0.43) | CES2MEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL16426168 | 0.82 | L3MBTL1 (0.45) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250115576-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2025-04-10 | — | — | US | disclosed |
| US-12209075-B2 | Pyridine-sulfonamide derivatives as sodium channel inhibitors | GENENTECH, INC. (US) | 2025-01-28 | — | — | US | disclosed |
| CN-117903071-A | Synthesis method of alpha-aminoketone derivative | 湖州师范学院 | 2024-04-19 | — | — | CN | disclosed |
| US-20230324797-A1 | POSITIVE RESIST COMPOSITION FOR EXTREME ULTRAVIOLET LITHOGRAPHY AND RESIST PATTERN FORMATION KIT FOR EXTREME ULTRAVIOLET LITHOGRAPHY | ZEON CORPORATION (JP) | 2023-10-12 | — | — | US | disclosed |
| US-20230324797-A1 | POSITIVE RESIST COMPOSITION FOR EXTREME ULTRAVIOLET LITHOGRAPHY AND RESIST PATTERN FORMATION KIT FOR EXTREME ULTRAVIOLET LITHOGRAPHY | ZEON CORPORATION (JP) | 2023-10-12 | — | — | US | disclosed |
| WO-2023189969-A1 | RESIST COMPOSITION AND METHOD FOR FORMING RESIST PATTERN | 日本ゼオン株式会社 | 2023-10-05 | — | — | WO | disclosed |
| US-20230288805-A1 | COPOLYMER, POSITIVE RESIST COMPOSITION, AND METHOD OF FORMING RESIST PATTERN | ZEON CORPORATION (JP) | 2023-09-14 | — | — | US | disclosed |
| US-20230288805-A1 | COPOLYMER, POSITIVE RESIST COMPOSITION, AND METHOD OF FORMING RESIST PATTERN | ZEON CORPORATION (JP) | 2023-09-14 | — | — | US | disclosed |
| US-11644752-B2 | Polymer, positive resist composition, and method of forming resist pattern | ZEON CORPORATION (JP) | 2023-05-09 | — | — | US | disclosed |
| US-11644752-B2 | Polymer, positive resist composition, and method of forming resist pattern | ZEON CORPORATION (JP) | 2023-05-09 | — | — | US | disclosed |
| CN-101781161-A | Method for preparing trifluoromethyl styrene compound | SHANGHAI CHEMEXPLORER CO LTD | 2010-07-21 | — | — | CN | disclosed |
| EP-0350069-B1 | METHOD FOR OXIDIZING UNSATURATED AROMATIC COMPOUNDS | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-5006151-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-04-09 | — | — | US | disclosed |
| US-4967009-A | REACTING UNSATURATED AROMATIC COMPOUNDS WITH AROMATIC IODOSYL COMPOUNDS TO YIELD AROMATIC ALDEHYDES OR KETONES | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| US-4929268-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0350069-A2 | Method for oxidizing unsaturated aromatic compounds | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4851594-A | HERBICIDES, POLYHALO SUBSTITUTED STYRENE INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| US-4629492-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1986-12-16 | — | — | US | disclosed |
| US-4085165-A | ISOCYANATE PREPOLYMER, VINYL COMPOUND, POLYAMINE OR POLYETHER CURING AGENT | BRIDGESTONE TIRE CO., LTD. (JA) | 1978-04-18 | — | — | US | disclosed |
| US-3932573-A | Process for producing glass fiber reinforced injection molding compounds | ETHYL CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12209075-B2 | Pyridine-sulfonamide derivatives as sodium channel inhibitors | SCN1B, CACNA1A, SCN1A | CES2 2259/4885MEN1 2471/4885KMT2A 1865/4885 |
| US-20250115576-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | F12, REN, ZYX | CES2 644/4885MEN1 81/4885KMT2A 3021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.