Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12425711 | 0.76 | — | — | |
| SCHEMBL543476 | 0.68 | — | — | |
| SCHEMBL5620989 | 0.67 | MAPT (0.40) | TSHRMEN1KMT2A | |
| SCHEMBL5620987 | 0.67 | MAPT (0.40) | TSHRMEN1KMT2A | |
| SCHEMBL19059633 | 0.65 | KDM4E (0.55) | AOC1KDM4EBLMNPSR1CYP3A4 | |
| SCHEMBL4965314 | 0.65 | — | — | |
| SCHEMBL1997770 | 0.64 | — | — | |
| SCHEMBL5238058 | 0.64 | AOC1 (0.50) | AOC1KDM4EBLMNPSR1CYP3A4 | |
| SCHEMBL10149598 | 0.64 | AOC1 (0.50) | AOC1KDM4EBLMNPSR1CYP3A4 | |
| SCHEMBL11469461 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |