Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.47 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.46 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.46 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.46 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SELP | P16109 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | F11 | P03951 | 2/20 | 0.44 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13486956 | 0.96 | PTPN1 (0.49) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL21778321 | 0.96 | PTPN1 (0.49) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL13672342 | 0.96 | PTPN1 (0.49) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL5981712 | 0.96 | PTPN1 (0.49) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL15095568 | 0.96 | PTPN1 (0.49) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL13151560 | 0.96 | PTPN1 (0.49) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL14440519 | 0.94 | PTPN1 (0.50) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL7150482 | 0.93 | LGALS8 (0.53) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL22984008 | 0.91 | PTPN1 (0.57) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL22983992 | 0.91 | PTPN1 (0.57) | PTPN1USP2MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10174132-B2 | Heparan sulfate synthesis | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2019-01-08 | — | — | US | disclosed |
| US-20160060365-A1 | HEPARAN SULFATE SYNTHESIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2016-03-03 | — | — | US | disclosed |
| US-20120142560-A1 | HEPARAN SULFATE SYNTHESIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174132-B2 | Heparan sulfate synthesis | HPSE, STT3B, DDOST | PTPN1 975/4885USP2 903/4885MEN1 2023/4885 |
| US-20160060365-A1 | HEPARAN SULFATE SYNTHESIS | HPSE, STT3B, DDOST | PTPN1 975/4885USP2 903/4885MEN1 2023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.