Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112204 | 0.71 | KDM4E (0.33) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL27941110 | 0.71 | TSHR (0.43) | TDP1ALDH1A1TSHRCASP1CYP3A4 | |
| SCHEMBL10432144 | 0.69 | DHFR (0.36) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL1002823 | 0.69 | KDM4E (0.42) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL18421930 | 0.67 | KDM4E (0.31) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16869681 | 0.65 | KDM4E (0.34) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL27770925 | 0.65 | CASP1 (0.42) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL293508 | 0.65 | PTK2 (0.38) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4284421 | 0.63 | CYP3A4 (0.44) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7350411 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |