Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027085 | 1.00 | POLB (0.50) | POLBCYP4A11CYP4F2KDM4EALDH1A1 | |
| SCHEMBL23266258 | 0.98 | POLB (0.51) | POLBCYP4A11CYP4F2KDM4EALDH1A1 | |
| SCHEMBL5355098 | 0.93 | POLB (0.53) | POLBCYP4A11CYP4F2KDM4EALDH1A1 | |
| SCHEMBL11683841 | 0.91 | POLB (0.51) | POLBCYP4A11CYP4F2KDM4EALDH1A1 | |
| SCHEMBL833204 | 0.85 | POLB (0.56) | POLBCYP4A11CYP4F2KDM4EALDH1A1 | |
| SCHEMBL8734047 | 0.84 | ESR1 (0.53) | POLBKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL26939981 | 0.84 | ESR1 (0.53) | POLBKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL19058769 | 0.84 | ESR1 (0.53) | POLBKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL4523904 | 0.83 | LTA4H (0.67) | POLBKDM4ELMNAACACBPPARA | |
| SCHEMBL9036580 | 0.82 | POLB (0.46) | POLBKDM4EALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |