SCHEMBL9112286

SCHEMBL9112286

C[C@](Cc1c[nH]nn1)([C@@H](N)C(=O)O)S(=O)O

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11113665 0.70 KDM4E (0.35)
SCHEMBL4272240 0.67 CYP1A2 (0.50) ALDH1A1MAPTPTGS1
SCHEMBL12493834 0.67 CYP1A2 (0.50) ALDH1A1MAPTPTGS1
SCHEMBL23356105 0.67 CYP1A2 (0.50) ALDH1A1MAPTPTGS1
SCHEMBL5960425 0.66
SCHEMBL28317315 0.65 MEN1 (0.35)
SCHEMBL846787 0.64 APAF1 (0.40) MAPT
SCHEMBL17275471 0.63 NOS2 (0.53)
SCHEMBL17275475 0.63 NOS2 (0.53)
SCHEMBL12493481 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0678095-A1 CRYSTALLINE PENICILLIN DERIVATIVE, AND ITS PRODUCTION AND USE TAIHO PHARMACEUTICAL CO., LTD. (JP) 1995-10-25 EP disclosed
WO-1995012601-A1 CRYSTALLINE PENICILLIN DERIVATIVE, AND ITS PRODUCTION AND USE TAIHO PHARMACEUTICAL CO., LTD. (JP) 1995-05-11 WO disclosed