SCHEMBL9112299

SCHEMBL9112299

CC(N)C(=O)O[Si](C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31
SLC7A5 Q01650 1/20 0.31
CHRNB2 P17787 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
CYP3A4 P08684 2/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8404068 1.00 SLC1A3 (0.31) SLC1A3SLC1A2SLC1A1GRIN2DGRIN3B
SCHEMBL10453588 1.00 SLC1A3 (0.31) SLC1A3SLC1A2SLC1A1GRIN2DGRIN3B
Hydrochloric Acid SCHEMBL8404062 0.97 LMNA (0.32) SLC1A3SLC1A2SLC1A1GRIN2DGRIN3B
Hydrochloric Acid SCHEMBL8404065 0.97 LMNA (0.32) SLC1A3SLC1A2SLC1A1GRIN2DGRIN3B
SCHEMBL17912254 0.81
SCHEMBL16540920 0.81
SCHEMBL17912253 0.81
SCHEMBL8401190 0.80 SLC7A5 (0.44) SLC1A3SLC1A2SLC1A1SLC7A5
SCHEMBL9235726 0.80 SLC7A5 (0.44) SLC1A3SLC1A2SLC1A1SLC7A5
Hydrochloric Acid SCHEMBL8401189 0.78 SLC7A5 (0.42) SLC1A3SLC1A2SLC1A1SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP claimed
US-20160200880-A1 MOISTURE CURABLE COMPOSITION WITH AMINO ACIDS MOMENTIVE PERFORMANCE MATERIALS INC. 2016-07-14 US claimed
EP-3039068-A1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS Momentive Performance Materials Inc. (US) 2016-07-06 EP claimed
CN-105683275-A Moisture curable compositions with amino acids 莫门蒂夫性能材料股份有限公司 2016-06-15 CN claimed
WO-2015031712-A1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-03-05 WO claimed
EP-0636117-A4 METHOD OF ADMINISTERING PYRUVATE AND METHODS OF SYNTHESIZING PYRUVATE PRECURSORS. ABBOTT LAB (US) 1995-07-26 EP claimed
EP-0636117-A1 USE OF PYRUVAMIDE AND SELECTED PYRUVYL-AMINO ACIDS ABBOTT LABORATORIES (US) 1995-02-01 EP claimed
WO-1993021147-A1 METHOD OF ADMINISTERING PYRUVATE AND METHODS OF SYNTHESIZING PYRUVATE PRECURSORS ABBOTT LABORATORIES (US) 1993-10-28 WO claimed
CN-113348185-B Modified conjugated diene polymer, method for producing same, and rubber composition containing same 株式会社LG化学 2023-08-01 CN disclosed
CN-113348185-A Modified conjugated diene polymer, method for producing same, and rubber composition containing same 株式会社LG化学 2021-09-03 CN disclosed
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP disclosed
CN-105683275-B Moisture curable compositions with amino acids 莫门蒂夫性能材料股份有限公司 2018-10-02 CN disclosed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US disclosed
US-20160200880-A1 MOISTURE CURABLE COMPOSITION WITH AMINO ACIDS MOMENTIVE PERFORMANCE MATERIALS INC. 2016-07-14 US disclosed
EP-3039068-A1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS Momentive Performance Materials Inc. (US) 2016-07-06 EP disclosed
CN-105683275-A Moisture curable compositions with amino acids 莫门蒂夫性能材料股份有限公司 2016-06-15 CN disclosed
WO-2015031712-A1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-03-05 WO disclosed