Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 4/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2247599 | 0.91 | NPC1 (0.62) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2240641 | 0.84 | RAB9A (0.67) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2249941 | 0.83 | RAB9A (0.68) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2244438 | 0.82 | NPC1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL11230016 | 0.80 | KDM4E (0.46) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL38661261 | 0.80 | NPC1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL1675514 | 0.79 | HDAC6 (0.56) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL11242605 | 0.79 | KDM4E (0.47) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL29479840 | 0.78 | PIK3CB (0.57) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL13568696 | 0.78 | HDAC6 (0.55) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623115-A4 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS. | DOW CHEMICAL CO (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0623115-A1 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014071-A1 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1993-07-22 | — | — | WO | disclosed |
| US-5216110-A | Monomers useful in nucleophilic displacement synthesis of polybenzazole polymers | THE DOW CHEMICAL COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| US-5194562-A | Nucleophilic displacement method for synthesis of non-rigid PBZ polymers | THE DOW CHEMICAL COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| US-5104960-A | Nucleophilic displacement method for synthesis of non-rigid PBZ polymers | THE DOW CHEMICAL COMPANY (US) | 1992-04-14 | — | — | US | disclosed |