Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 8/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 8/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 6/20 | 0.46 |
| ▸ | HSPE1 | P61604 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | UTRN | P46939 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242605 | 0.99 | KDM4E (0.47) | KDM4EALDH1A1KMT2ANPC1MEN1 | |
| SCHEMBL325885 | 0.86 | ESR1 (0.57) | KDM4EALDH1A1KMT2ANPC1MEN1 | |
| SCHEMBL14614442 | 0.81 | PTPN1 (0.52) | KDM4EALDH1A1KMT2ANPC1MEN1 | |
| SCHEMBL9112458 | 0.80 | NPC1 (0.61) | KDM4EALDH1A1NPC1HPGDHTT | |
| SCHEMBL2240641 | 0.80 | RAB9A (0.67) | KDM4EALDH1A1KMT2ANPC1MEN1 | |
| SCHEMBL13994723 | 0.80 | PTPN1 (0.57) | KDM4EALDH1A1KMT2ANPC1MEN1 | |
| SCHEMBL11238508 | 0.80 | RAB9A (0.66) | KDM4EALDH1A1KMT2ANPC1MEN1 | |
| SCHEMBL2242855 | 0.80 | PTPN2 (0.64) | KDM4EALDH1A1KMT2ANPC1HPGD | |
| SCHEMBL1675514 | 0.80 | HDAC6 (0.56) | KDM4EALDH1A1KMT2ANPC1MEN1 | |
| SCHEMBL11385246 | 0.79 | PTGS2 (0.45) | KDM4EALDH1A1KMT2AHDAC6UTRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250315-A | 2-(SUBSTITUTED AMINO-PHENYL), SULFONIC ACID SUBSTITUTED | HOFFMANN-LA ROCHE INC. (US) | 1981-02-10 | — | — | US | claimed |
| EP-0012178-A1 | Benzoxazol derivatives, methods for their preparation, cosmetic compositions containing such compounds, use of such compounds as UV-A filters and method of protecting the skin and hair and method of stabilizing cosmetic compositions | Richardson-Vicks, Inc. (US) | 1980-06-25 | — | — | EP | claimed |
| EP-0012178-B1 | BENZOXAZOL DERIVATIVES, METHODS FOR THEIR PREPARATION, COSMETIC COMPOSITIONS CONTAINING SUCH COMPOUNDS, USE OF SUCH COMPOUNDS AS UV-A FILTERS AND METHOD OF PROTECTING THE SKIN AND HAIR AND METHOD OF STABILIZING COSMETIC COMPOSITIONS | Richardson-Vicks, Inc. (US) | 1982-12-08 | — | — | EP | disclosed |
| US-4250315-A | 2-(SUBSTITUTED AMINO-PHENYL), SULFONIC ACID SUBSTITUTED | HOFFMANN-LA ROCHE INC. (US) | 1981-02-10 | — | — | US | disclosed |