Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | YWHAG | P61981 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336439 | 0.85 | KDM4E (0.76) | MEN1KMT2AMAPTKDM4ETHRB | |
| SCHEMBL6254176 | 0.84 | HTT (0.77) | MEN1KMT2AMAPTKDM4ETHRB | |
| SCHEMBL11610621 | 0.84 | HTT (0.77) | MEN1KMT2AMAPTKDM4ETHRB | |
| SCHEMBL29805092 | 0.81 | LMNA (0.50) | MAPTKDM4EHSD17B10HTTTOP2A | |
| SCHEMBL2855312 | 0.81 | SMN1; SMN2 (0.60) | MEN1KMT2AMAPTKDM4ETHRB | |
| SCHEMBL23546131 | 0.81 | HTR3A (0.50) | ALDH1A1CYP3A4CYP2C9PTGS2HTR6 | |
| SCHEMBL20141454 | 0.81 | LMNA (0.50) | MAPTKDM4EHSD17B10HTTTOP2A | |
| SCHEMBL11100139 | 0.81 | KDM4E (0.56) | MEN1KMT2AMAPTKDM4ETHRB | |
| SCHEMBL9113476 | 0.81 | KDM4E (0.58) | MEN1KMT2AMAPTKDM4ETHRB | |
| SCHEMBL9113475 | 0.80 | GAA (0.52) | MEN1KMT2AMAPTKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995017471-A1 | DISAZO COMPOUND | ZENECA LIMITED (GB) | 1995-06-29 | — | — | WO | claimed |
| WO-1995017472-A1 | DISAZO COMPOUND | ZENECA LIMITED (GB) | 1995-06-29 | — | — | WO | claimed |
| US-5453495-A | Disazo compounds containing an optionally substituted piperazinyl group | ZENECA LIMITED (GB) | 1995-09-26 | — | — | US | disclosed |
| WO-1995017471-A1 | DISAZO COMPOUND | ZENECA LIMITED (GB) | 1995-06-29 | — | — | WO | disclosed |
| WO-1995017472-A1 | DISAZO COMPOUND | ZENECA LIMITED (GB) | 1995-06-29 | — | — | WO | disclosed |