Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 12/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.56 |
| ▸ | MAPT | P10636 | 10/20 | 0.56 |
| ▸ | NPC1 | O15118 | 10/20 | 0.56 |
| ▸ | RAB9A | P51151 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | HPGD | P15428 | 8/20 | 0.56 |
| ▸ | PKM | P14618 | 4/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148043 | 0.85 | NPC1 (0.75) | SMN1; SMN2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL7653231 | 0.83 | SMN1; SMN2 (0.56) | PRMT1SMN1; SMN2KDM4EMAPTNPC1 | |
| SCHEMBL7652952 | 0.83 | SMN1; SMN2 (0.56) | PRMT1SMN1; SMN2KDM4EMAPTNPC1 | |
| SCHEMBL7652960 | 0.83 | KDM4E (0.61) | SMN1; SMN2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL8174405 | 0.83 | KDM4E (0.61) | SMN1; SMN2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL9113986 | 0.81 | PRMT1 (0.56) | PRMT1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL21011385 | 0.79 | NPC1 (0.70) | PRMT1SMN1; SMN2KDM4EMAPTNPC1 | |
| SCHEMBL7652411 | 0.78 | MMP13 (0.73) | SMN1; SMN2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL2361964 | 0.78 | ALDH1A1 (0.52) | PRMT1SMN1; SMN2KDM4EMAPTNPC1 | |
| SCHEMBL7652407 | 0.78 | MMP13 (0.56) | PRMT1SMN1; SMN2KDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995008540-A1 | BIS(AMIDINOBENZIMIDAZOLYL)ALKANES AS ANTIVIRAL AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-03-30 | — | — | WO | disclosed |