Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18677307 | 0.82 | CTSA (0.40) | CTSAACHEKDM4ETDP1LMNA | |
| SCHEMBL21131941 | 0.80 | CTSA (0.39) | CTSAACHEKDM4ETDP1LMNA | |
| SCHEMBL21096102 | 0.80 | CTSA (0.39) | CTSAACHEKDM4ETDP1LMNA | |
| SCHEMBL8049721 | 0.78 | LMNA (0.52) | CTSAACHEKDM4ETDP1LMNA | |
| SCHEMBL9193627 | 0.77 | CTSA (0.40) | CTSAACHEKDM4ETDP1LMNA | |
| SCHEMBL20311978 | 0.77 | — | — | |
| SCHEMBL17375881 | 0.77 | LAP3 (0.33) | FDPS | |
| SCHEMBL9188718 | 0.75 | CTSA (0.39) | CTSAACHEKDM4ETDP1LMNA | |
| SCHEMBL18307659 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL9239802 | 0.73 | CTSA (0.37) | CTSAACHEKDM4ETDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359115-A | Reacting phosphonic monoester with dialkylazodicarboxylate, triphenylphosphine and secondary alcohol to form diester, hydrolyzing selective ester to form monoester, coupling an aminoacid to yield peptidylphosphonate | AFFYMAX TECHNOLOGIES, N.V. (US) | 1994-10-25 | — | — | US | claimed |
| CN-120118122-A | Organic phosphonate flame retardant, and synthetic method and application thereof | 威海海润新材料科技有限公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-0659188-A4 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS. | AFFYMAX TECH NV (AN) | 1995-11-22 | — | — | EP | disclosed |
| EP-0659188-A1 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-06-28 | — | — | EP | disclosed |
| US-5420328-A | Esterification with alcohol and hydrolysis | AFFYMAX TECHNOLOGIES, N.V. (AN) | 1995-05-30 | — | — | US | disclosed |
| US-5359115-A | Reacting phosphonic monoester with dialkylazodicarboxylate, triphenylphosphine and secondary alcohol to form diester, hydrolyzing selective ester to form monoester, coupling an aminoacid to yield peptidylphosphonate | AFFYMAX TECHNOLOGIES, N.V. (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1994006808-A1 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1994-03-31 | — | — | WO | disclosed |