SCHEMBL9112774

SCHEMBL9112774

CCS[C@@H]1O[C@@H]2COC(c3ccccc3)O[C@H]2[C@H](OCc2ccccc2)[C@H]1OC(=O)CCC(C)=O

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
SELP P16109 1/20 0.40
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
BCHE P06276 2/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19614247 1.00 L3MBTL1 (0.50) L3MBTL1SELPKMT2AMEN1BCHE
SCHEMBL535845 1.00 L3MBTL1 (0.50) L3MBTL1SELPKMT2AMEN1BCHE
SCHEMBL19614246 1.00 L3MBTL1 (0.50) L3MBTL1SELPKMT2AMEN1BCHE
SCHEMBL15196691 0.90 L3MBTL1 (0.54) L3MBTL1SELPKMT2AMEN1BCHE
SCHEMBL20626555 0.90 L3MBTL1 (0.54) L3MBTL1SELPKMT2AMEN1BCHE
SCHEMBL9908823 0.90 L3MBTL1 (0.54) L3MBTL1SELPKMT2AMEN1BCHE
SCHEMBL9110670 0.90 L3MBTL1 (0.54) L3MBTL1SELPKMT2AMEN1BCHE
SCHEMBL535106 0.90 L3MBTL1 (0.54) L3MBTL1SELPKMT2AMEN1BCHE
SCHEMBL7145164 0.88 L3MBTL1 (0.50) L3MBTL1SELPKMT2AMEN1BCHE
SCHEMBL26492359 0.87 L3MBTL1 (0.50) L3MBTL1SELPKMT2AMEN1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10174132-B2 Heparan sulfate synthesis UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2019-01-08 US disclosed
US-20160060365-A1 HEPARAN SULFATE SYNTHESIS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2016-03-03 US disclosed
US-20120142560-A1 HEPARAN SULFATE SYNTHESIS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10174132-B2 Heparan sulfate synthesis HPSE, STT3B, DDOST L3MBTL1 3217/4885SELP 682/4885KMT2A 2909/4885
US-20160060365-A1 HEPARAN SULFATE SYNTHESIS HPSE, STT3B, DDOST L3MBTL1 3217/4885SELP 682/4885KMT2A 2909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.