Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112784 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDHTTSIGMAR1 | |
| SCHEMBL6158455 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDHTTL3MBTL1 | |
| SCHEMBL10344075 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDHTTSIGMAR1 | |
| SCHEMBL3125891 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDHTTSIGMAR1 | |
| SCHEMBL876143 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TSHRHPGDHTTSIGMAR1 | |
| SCHEMBL13600490 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRHPGDSIGMAR1MEN1 | |
| SCHEMBL3202573 | 0.79 | ALDH1A1 (0.72) | ALDH1A1TSHRHPGDHTTSIGMAR1 | |
| SCHEMBL2373020 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDHTTSIGMAR1 | |
| SCHEMBL6158453 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDHTTSIGMAR1 | |
| SCHEMBL23298373 | 0.76 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDHTTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |