Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CCND1 | P24385 | 1/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 7/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112828 | 1.00 | TRPA1 (0.52) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL4630799 | 0.80 | TRPA1 (0.54) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL30528037 | 0.80 | TRPA1 (0.54) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL229461 | 0.80 | TRPA1 (0.54) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL13158791 | 0.80 | TRPA1 (0.54) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL347781 | 0.78 | TRPA1 (0.52) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL2141776 | 0.78 | TRPA1 (0.52) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL2041527 | 0.78 | TRPA1 (0.52) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL12425707 | 0.78 | TRPA1 (0.52) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL16884916 | 0.78 | TRPA1 (0.52) | TRPA1NFKB1CDK4CCND1JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |