Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112933 | 1.00 | TBXAS1 (0.46) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL9113306 | 0.89 | TERT (0.44) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL9113295 | 0.89 | TERT (0.44) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL27582835 | 0.81 | TBXAS1 (0.49) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL18019076 | 0.78 | TBXAS1 (0.43) | TBXAS1TERTALOX15TAAR1HTR1A | |
| SCHEMBL9777191 | 0.78 | TBXAS1 (0.60) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL3431746 | 0.78 | TBXAS1 (0.66) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL6583649 | 0.78 | TBXAS1 (0.53) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL6158703 | 0.77 | — | — | |
| SCHEMBL27191626 | 0.76 | TBXAS1 (0.51) | TBXAS1TERTALOX15TAAR1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |