Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 2/20 | 0.70 |
| ▸ | MAOB | P27338 | 5/20 | 0.58 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.48 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9113139 | 1.00 | PAM (0.70) | PAMMAOBPTGER4PTGER3PTGER2 | |
| SCHEMBL4296099 | 0.83 | PAM (0.76) | PAMMAOBPTGER4PTGER3PTGER2 | |
| SCHEMBL156767 | 0.83 | PAM (1.00) | PAMMAOBPTGER4PTGER3PTGER2 | |
| SCHEMBL582727 | 0.83 | PAM (1.00) | PAMMAOBPTGER4PTGER3PTGER2 | |
| SCHEMBL4296095 | 0.83 | PAM (0.76) | PAMMAOBPTGER4PTGER3PTGER2 | |
| SCHEMBL2148302 | 0.83 | PAM (1.00) | PAMMAOBPTGER4PTGER3PTGER2 | |
| Hydrochloric Acid SCHEMBL28759894 | 0.81 | PAM (0.96) | PAMMAOBPTGER4PTGER3PTGER2 | |
| SCHEMBL387249 | 0.81 | PAM (0.96) | PAMMAOBPTGER4PTGER3PTGER2 | |
| Ammonia Solution, Strong SCHEMBL6327623 | 0.81 | PAM (0.96) | PAMMAOBPTGER4PTGER3PTGER2 | |
| Ammonia Solution, Strong SCHEMBL6327618 | 0.81 | PAM (0.96) | PAMMAOBPTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |