Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TGM2 | P21980 | 5/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11430193 | 0.99 | CA12 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23577870 | 0.88 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL22380701 | 0.83 | PDPK1 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30901337 | 0.82 | IDO1 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2241739 | 0.80 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7417096 | 0.79 | AKR1B1 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5846673 | 0.78 | MAPT (0.68) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12273071 | 0.77 | TGM2 (0.56) | ALDH1A1TGM2IDO1TDO2CES1 | |
| SCHEMBL1680517 | 0.77 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1050601 | 0.76 | SMYD3 (0.56) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4186132-A | Isatin products | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1980-01-29 | — | — | US | claimed |
| US-5441955-A | Tuberculosis | PATHOGENESIS CORPORATION (US) | 1995-08-15 | — | — | US | disclosed |
| WO-1995013807-A1 | INDOLO[2,1-b]QUINAZOLINE-6,12-DIONE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | PATHOGENESIS CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |
| US-4252723-A | Air oxidation of oxindoles to isatins | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1981-02-24 | — | — | US | disclosed |
| US-4188325-A | Isatin process and products | REGENTS OF UNIVERSITY OF MINNESOTA (US) | 1980-02-12 | — | — | US | disclosed |
| US-4186132-A | Isatin products | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1980-01-29 | — | — | US | disclosed |