Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | MDH2 | P40926 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27215450 | 0.90 | IDO1 (0.47) | IDO1TDO2ALDH1A1POLBCDK1 | |
| SCHEMBL27214660 | 0.90 | IDO1 (0.47) | IDO1TDO2ALDH1A1POLBCDK1 | |
| SCHEMBL9113250 | 0.82 | CA12 (0.50) | IDO1TDO2CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL11430193 | 0.81 | CA12 (0.49) | IDO1TDO2CA12CA1CA2 | |
| SCHEMBL27214668 | 0.81 | IDO1 (0.40) | IDO1TDO2RXFP1POLBPDPK1 | |
| SCHEMBL27231252 | 0.81 | IDO1 (0.40) | IDO1TDO2RXFP1POLBPDPK1 | |
| SCHEMBL3152862 | 0.77 | SMN1; SMN2 (0.49) | IDO1TDO2RXFP1ALDH1A1MAPK1 | |
| SCHEMBL3152850 | 0.77 | SMN1; SMN2 (0.49) | IDO1TDO2RXFP1ALDH1A1MAPK1 | |
| SCHEMBL7013721 | 0.77 | IDO1 (0.46) | IDO1TDO2RXFP1ALDH1A1HSD17B10 | |
| SCHEMBL2241739 | 0.75 | CA12 (0.54) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150368-A1 | ULK INHIBITORS AND METHODS OF USE THEREOF | DECIPHERA PHARMACEUTICALS, LLC | 2024-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150368-A1 | ULK INHIBITORS AND METHODS OF USE THEREOF | ULK1, ULK2, ULK3 | IDO1 3772/4885TDO2 4251/4885CA12 4743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.